Cognitive Improvement Through Non-Invasive Brain Stimulation Techniques in Healthy Adults
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Cognitive enhancement is an effort to improve or improve mental functions such as memory, attention, problem solving, language, and other thinking skills. In healthy adults, the goal of cognitive enhancement is to improve current mental abilities, increase productivity, and prolong periods of mental clarity. This research was conducted with the aim of exploring various non-invasive brain stimulation techniques such as tDCS, TMS, and tACS, which offer innovative ways to improve various aspects of cognitive function without the need for invasive procedures. While there are many potential benefits, it is important to understand the long-term effects, optimize use methods, and ensure use of this technology is safe and ethical. The method used by researchers in researching Cognitive Improvement Through Non-Invasive Brain Stimulation Techniques in Healthy Adults is to use a quantitative method. The data obtained by researchers was obtained from the results of distributing questionnaires. The distribution of questionnaires carried out by researchers was carried out online using Google From software. The results of data acquisition will also be tested again using the SPSS application. From the research results, it can be seen that this research is an interesting and continuously developing field in neuroscience and psychology today. With non-invasive brain stimulation techniques, it is possible to stimulate certain areas of the brain, thereby further improving cognitive functions such as memory, attention and problem solving in healthy adults. From this study, researchers can conclude that non-invasive brain stimulation, such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), has been proven to improve motor and cognitive function in healthy adults. Recent research shows that tDCS can modulate the brain's motor cortex, which functions to increase intelligence in healthy adults.
Ahmed, I., Mustafaoglu, R., Rossi, S., Cavdar, F. A., Agyenkwa, S. K., Pang, M. Y. C., & Straudi, S. (2023). Non-invasive Brain Stimulation Techniques for the Improvement of Upper Limb Motor Function and Performance in Activities of Daily Living After Stroke: A Systematic Review and Network Meta-analysis. Archives of Physical Medicine and Rehabilitation, 104(10), 1683–1697. https://doi.org/10.1016/j.apmr.2023.04.027
Bae, E. S., & Kang, H. S. (2022). Effect of a Physical-Strengthening Exercise Program on Physical Fitness, Depression, and Cognitive Function in Older Patients with Parkinson’s Disease: A Cross-Sectional Study. Journal of Korean Gerontological Nursing, 24(3), 278–290. https://doi.org/10.17079/jkgn.2022.24.3.278
Begemann, M. J., Brand, B. A., ?ur?i?-Blake, B., Aleman, A., & Sommer, I. E. (2020). Efficacy of non-invasive brain stimulation on cognitive functioning in brain disorders: A meta-analysis. Psychological Medicine, 50(15), 2465–2486. https://doi.org/10.1017/S0033291720003670
Benjamin, E. J., Muntner, P., Alonso, A., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Chang, A. R., Cheng, S., Das, S. R., Delling, F. N., Djousse, L., Elkind, M. S. V., Ferguson, J. F., Fornage, M., Jordan, L. C., Khan, S. S., Kissela, B. M., Knutson, K. L., … On behalf of the American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. (2019). Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association. Circulation, 139(10). https://doi.org/10.1161/CIR.0000000000000659
Breitling, C., Zaehle, T., Dannhauer, M., Tegelbeckers, J., Flechtner, H.-H., & Krauel, K. (2020). Comparison between conventional and HD-tDCS of the right inferior frontal gyrus in children and adolescents with ADHD. Clinical Neurophysiology, 131(5), 1146–1154. https://doi.org/10.1016/j.clinph.2019.12.412
Brighina, F., Raieli, V., Messina, L. M., Santangelo, G., Puma, D., Drago, F., Rocchitelli, L., Vanadia, F., Giglia, G., & Mangano, S. (2019). Non-invasive Brain Stimulation in Pediatric Migraine: A Perspective From Evidence in Adult Migraine. Frontiers in Neurology, 10, 364. https://doi.org/10.3389/fneur.2019.00364
Brookman-Frazee, L., Stadnick, N., Chlebowski, C., Baker-Ericzén, M., & Ganger, W. (2018). Characterizing psychiatric comorbidity in children with autism spectrum disorder receiving publicly funded mental health services. Autism, 22(8), 938–952. https://doi.org/10.1177/1362361317712650
Cassani, R., Novak, G. S., Falk, T. H., & Oliveira, A. A. (2020). Virtual reality and non-invasive brain stimulation for rehabilitation applications: A systematic review. Journal of NeuroEngineering and Rehabilitation, 17(1), 147. https://doi.org/10.1186/s12984-020-00780-5
Casula, A., Milazzo, B. M., Martino, G., Sergi, A., Lucifora, C., Tomaiuolo, F., Quartarone, A., Nitsche, M. A., & Vicario, C. M. (2023). Non-Invasive Brain Stimulation for the Modulation of Aggressive Behavior—A Systematic Review of Randomized Sham-Controlled Studies. Life, 13(5), 1220. https://doi.org/10.3390/life13051220
Curran-Everett, D. (2018). Explorations in statistics: The log transformation. Advances in Physiology Education, 42(2), 343–347. https://doi.org/10.1152/advan.00018.2018
Dell’Osso, B., & Di Lorenzo, G. (Eds.). (2020). Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences. Springer International Publishing. https://doi.org/10.1007/978-3-030-43356-7
Fitzgerald, P. B., Gill, S., Hussain, S., Sarma, S., Chamoli, S., Weiss, A., Garside, D., Purushothaman, S., Fasnacht, M., Simpson, B., Csizmadia, T., Dean, C., & Loo, C. (2021). The place of non-invasive brain stimulation in the RANZCP clinical practice guidelines for mood disorders. Australian & New Zealand Journal of Psychiatry, 55(4), 349–354. https://doi.org/10.1177/00048674211004344
Fond, G., Nemani, K., Etchecopar-Etchart, D., Loundou, A., Goff, D. C., Lee, S. W., Lancon, C., Auquier, P., Baumstarck, K., Llorca, P.-M., Yon, D. K., & Boyer, L. (2021). Association Between Mental Health Disorders and Mortality Among Patients With COVID-19 in 7 Countries: A Systematic Review and Meta-analysis. JAMA Psychiatry, 78(11), 1208. https://doi.org/10.1001/jamapsychiatry.2021.2274
Fritz, T. (2020). A synthetic approach to Markov kernels, conditional independence and theorems on sufficient statistics. Advances in Mathematics, 370, 107239. https://doi.org/10.1016/j.aim.2020.107239
Fröhlich, F., & Lustenberger, C. (2020). Neuromodulation of sleep rhythms in schizophrenia: Towards the rational design of non-invasive brain stimulation. Schizophrenia Research, 221, 71–80. https://doi.org/10.1016/j.schres.2020.04.003
Gilam, G., Abend, R., Gurevitch, G., Erdman, A., Baker, H., Ben-Zion, Z., & Hendler, T. (2018). Attenuating anger and aggression with neuromodulation of the vmPFC: A simultaneous tDCS-fMRI study. Cortex, 109, 156–170. https://doi.org/10.1016/j.cortex.2018.09.010
Griffen, C., Duncan, M., Hattersley, J., Weickert, M. O., Dallaway, A., & Renshaw, D. (2022). Effects of resistance exercise and whey protein supplementation on skeletal muscle strength, mass, physical function, and hormonal and inflammatory biomarkers in healthy active older men: A randomised, double-blind, placebo-controlled trial. Experimental Gerontology, 158, 111651. https://doi.org/10.1016/j.exger.2021.111651
Guerra, A., López-Alonso, V., Cheeran, B., & Suppa, A. (2020). Variability in non-invasive brain stimulation studies: Reasons and results. Neuroscience Letters, 719, 133330. https://doi.org/10.1016/j.neulet.2017.12.058
Henley, S. J., Ward, E. M., Scott, S., Ma, J., Anderson, R. N., Firth, A. U., Thomas, C. C., Islami, F., Weir, H. K., Lewis, D. R., Sherman, R. L., Wu, M., Benard, V. B., Richardson, L. C., Jemal, A., Cronin, K., & Kohler, B. A. (2020). Annual report to the nation on the status of cancer, part I: National cancer statistics. Cancer, 126(10), 2225–2249. https://doi.org/10.1002/cncr.32802
Hernando, A., Galvez, F., García, M. A., Soto-León, V., Alonso-Bonilla, C., Aguilar, J., & Oliviero, A. (2020). Effects of Moderate Static Magnetic Field on Neural Systems Is a Non-invasive Mechanical Stimulation of the Brain Possible Theoretically? Frontiers in Neuroscience, 14, 419. https://doi.org/10.3389/fnins.2020.00419
Hirsch, D. A., Was, C. A., & Graham, E. N. (2021). Unique Mechanisms for the Availability of Declarative Memory Elements and the Strengthening of Cognitive Operations. Advances in Cognitive Psychology, 17(2), 149–160. https://doi.org/10.5709/acp-0325-3
Holscher, H., Taylor, A., Swanson, K., Novotny, J., & Baer, D. (2018). Almond Consumption and Processing Affects the Composition of the Gastrointestinal Microbiota of Healthy Adult Men and Women: A Randomized Controlled Trial. Nutrients, 10(2), 126. https://doi.org/10.3390/nu10020126
Horn, A., Wenzel, G., Irmen, F., Huebl, J., Li, N., Neumann, W.-J., Krause, P., Bohner, G., Scheel, M., & Kühn, A. A. (2019). Deep brain stimulation induced normalization of the human functional connectome in Parkinson’s disease. Brain, 142(10), 3129–3143. https://doi.org/10.1093/brain/awz239
Huo, L., Zhu, X., Zheng, Z., Ma, J., Ma, Z., Gui, W., & Li, J. (2021). Effects of Transcranial Direct Current Stimulation on Episodic Memory in Older Adults: A Meta-analysis. The Journals of Gerontology: Series B, 76(4), 692–702. https://doi.org/10.1093/geronb/gbz130
Iorfino, F., Scott, E. M., Carpenter, J. S., Cross, S. P., Hermens, D. F., Killedar, M., Nichles, A., Zmicerevska, N., White, D., Guastella, A. J., Scott, J., McGorry, P. D., & Hickie, I. B. (2019). Clinical Stage Transitions in Persons Aged 12 to 25 Years Presenting to Early Intervention Mental Health Services With Anxiety, Mood, and Psychotic Disorders. JAMA Psychiatry, 76(11), 1167. https://doi.org/10.1001/jamapsychiatry.2019.2360
Jayaram, P., Yeh, P., Patel, S. J., Cela, R., Shybut, T. B., Grol, M. W., & Lee, B. H. (2019). Effects of Aspirin on Growth Factor Release From Freshly Isolated Leukocyte-Rich Platelet-Rich Plasma in Healthy Men: A Prospective Fixed-Sequence Controlled Laboratory Study. The American Journal of Sports Medicine, 47(5), 1223–1229. https://doi.org/10.1177/0363546519827294
Jung, S., Choe, S., Woo, H., Jeong, H., An, H.-K., Moon, H., Ryu, H. Y., Yeo, B. K., Lee, Y. W., Choi, H., Mun, J. Y., Sun, W., Choe, H. K., Kim, E.-K., & Yu, S.-W. (2020). Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits. Autophagy, 16(3), 512–530. https://doi.org/10.1080/15548627.2019.1630222
Kim, T., Kim, H. J., Choi, W., Lee, Y. M., Pyo, J. H., Lee, J., Kim, J., Kim, J., Kim, J.-H., Kim, C., & Kim, W. J. (2022). Deep brain stimulation by blood–brain-barrier-crossing piezoelectric nanoparticles generating current and nitric oxide under focused ultrasound. Nature Biomedical Engineering, 7(2), 149–163. https://doi.org/10.1038/s41551-022-00965-4
Kuhn, H. G., Toda, T., & Gage, F. H. (2018). Adult Hippocampal Neurogenesis: A Coming-of-Age Story. The Journal of Neuroscience, 38(49), 10401–10410. https://doi.org/10.1523/JNEUROSCI.2144-18.2018
Lamaziere, A., Rainteau, D., Kc, P., Humbert, L., Gauliard, E., Ichou, F., Ponnaiah, M., Bouby, N., Salem, J.-E., Mallet, J.-M., Guerin, M., & Lesnik, P. (2020). Distinct Postprandial Bile Acids Responses to a High-Calorie Diet in Men Volunteers Underscore Metabolically Healthy and Unhealthy Phenotypes. Nutrients, 12(11), 3545. https://doi.org/10.3390/nu12113545
Lewis, Y. D., Gallop, L., Campbell, I. C., & Schmidt, U. (2021). Effects of non-invasive brain stimulation in children and young people with psychiatric disorders: A protocol for a systematic review. Systematic Reviews, 10(1), 76. https://doi.org/10.1186/s13643-021-01627-3
Liebrand, M., Karabanov, A., Antonenko, D., Flöel, A., Siebner, H. R., Classen, J., Krämer, U. M., & Tzvi, E. (2020). Beneficial effects of cerebellar tDCS on motor learning are associated with altered putamen-cerebellar connectivity: A simultaneous tDCS-fMRI study. NeuroImage, 223, 117363. https://doi.org/10.1016/j.neuroimage.2020.117363
Liu, L., Dong, Y., Kong, M., Zhou, J., Zhao, H., Tang, Z., Zhang, M., & Wang, Z. (2020). Insights into the long-term pollution trends and sources contributions in Lake Taihu, China using multi-statistic analyses models. Chemosphere, 242, 125272. https://doi.org/10.1016/j.chemosphere.2019.125272
Lopez, A. D., & Adair, T. (2019). Is the long-term decline in cardiovascular-disease mortality in high-income countries over? Evidence from national vital statistics. International Journal of Epidemiology, 48(6), 1815–1823. https://doi.org/10.1093/ije/dyz143
Mishra, R. K., & Thrasher, A. T. (2021). Transcranial direct current stimulation of dorsolateral prefrontal cortex improves dual-task gait performance in patients with Parkinson’s disease: A double blind, sham-controlled study. Gait & Posture, 84, 11–16. https://doi.org/10.1016/j.gaitpost.2020.11.012
Moxon, S. R., Corbett, N. J., Fisher, K., Potjewyd, G., Domingos, M., & Hooper, N. M. (2019). Blended alginate/collagen hydrogels promote neurogenesis and neuronal maturation. Materials Science and Engineering: C, 104, 109904. https://doi.org/10.1016/j.msec.2019.109904
Muhammad, R. U., & Anwary, A. (2019). Archieve Media Promotion for Collective Memory Safety on Digital Natives Generations. Record and Library Journal, 5(1), 50. https://doi.org/10.20473/rlj.V5-I1.2019.50-61
Natarajan, P., Skidmore, J., Aduroja, O., Kunam, V., & Schuller, D. (2021). Bilateral pneumatoceles resulting in spontaneous bilateral pneumothoraces and secondary infection in a previously healthy man with COVID-19. Baylor University Medical Center Proceedings, 34(5), 590–592. https://doi.org/10.1080/08998280.2021.1927410
Neri, F., Mencarelli, L., Menardi, A., Giovannelli, F., Rossi, S., Sprugnoli, G., Rossi, A., Pascual-Leone, A., Salvador, R., Ruffini, G., & Santarnecchi, E. (2020). A novel tDCS sham approach based on model-driven controlled shunting. Brain Stimulation, 13(2), 507–516. https://doi.org/10.1016/j.brs.2019.11.004
Noll, J., & Tackett, M. (2023). Insights from DATAFEST point to new opportunities for undergraduate statistics courses: Team collaborations, designing research questions, and data ethics. Teaching Statistics, 45(S1). https://doi.org/10.1111/test.12345
Plym, A., Zhang, Y., Stopsack, K. H., Delcoigne, B., Wiklund, F., Haiman, C., Kenfield, S. A., Kibel, A. S., Giovannucci, E., Penney, K. L., & Mucci, L. A. (2023). A Healthy Lifestyle in Men at Increased Genetic Risk for Prostate Cancer. European Urology, 83(4), 343–351. https://doi.org/10.1016/j.eururo.2022.05.008
Rose, B. D., Bitarafan, V., Rezaie, P., Fitzgerald, P. C. E., Horowitz, M., & Feinle-Bisset, C. (2021). Comparative Effects of Intragastric and Intraduodenal Administration of Quinine on the Plasma Glucose Response to a Mixed-Nutrient Drink in Healthy Men: Relations with Glucoregulatory Hormones and Gastric Emptying. The Journal of Nutrition, 151(6), 1453–1461. https://doi.org/10.1093/jn/nxab020
Schladitz, K., Förster, F., Wagner, M., Heser, K., König, H.-H., Hajek, A., Wiese, B., Pabst, A., Riedel-Heller, S. G., & Löbner, M. (2022). Gender Specifics of Healthy Ageing in Older Age as Seen by Women and Men (70+): A Focus Group Study. International Journal of Environmental Research and Public Health, 19(5), 3137. https://doi.org/10.3390/ijerph19053137
Serio, C., Gabarda, A., Uyar-Morency, F., Silfee, V., Ludwig, J., Szigethy, E., & Butterworth, S. (2022). Strengthening the Impact of Digital Cognitive Behavioral Interventions Through a Dual Intervention: Proficient Motivational Interviewing–Based Health Coaching Plus In-Application Techniques. JMIR Formative Research, 6(5), e34552. https://doi.org/10.2196/34552
Sharma, M., Lowry, A. C., Rao, S. S., Whitehead, W. E., Szarka, L. A., Hamilton, F. A., & Bharucha, A. E. (2021). A multicenter study of anorectal pressures and rectal sensation measured with portable manometry in healthy women and men. Neurogastroenterology & Motility, 33(6), e14067. https://doi.org/10.1111/nmo.14067
Siebner, H. R., Funke, K., Aberra, A. S., Antal, A., Bestmann, S., Chen, R., Classen, J., Davare, M., Di Lazzaro, V., Fox, P. T., Hallett, M., Karabanov, A. N., Kesselheim, J., Beck, M. M., Koch, G., Liebetanz, D., Meunier, S., Miniussi, C., Paulus, W., … Ugawa, Y. (2022). Transcranial magnetic stimulation of the brain: What is stimulated? – A consensus and critical position paper. Clinical Neurophysiology, 140, 59–97. https://doi.org/10.1016/j.clinph.2022.04.022
Trebeau Crogman, M., & Crogman, H. (2020). Popularizing Visuo-Spatial Training for Reading Challenges: A Call to Experts in Support of Language and Non-language-based Cognitive Skills Strengthening. Frontiers in Education, 5, 153. https://doi.org/10.3389/feduc.2020.00153
Vignaud, P., Mondino, M., Poulet, E., Palm, U., & Brunelin, J. (2018). Duration but not intensity influences transcranial direct current stimulation (tDCS) after-effects on cortical excitability. Neurophysiologie Clinique, 48(2), 89–92. https://doi.org/10.1016/j.neucli.2018.02.001
Vigo, D. V., Kestel, D., Pendakur, K., Thornicroft, G., & Atun, R. (2019). Disease burden and government spending on mental, neurological, and substance use disorders, and self-harm: Cross-sectional, ecological study of health system response in the Americas. The Lancet Public Health, 4(2), e89–e96. https://doi.org/10.1016/S2468-2667(18)30203-2
Westwood, S. J., Criaud, M., Lam, S.-L., Lukito, S., Wallace-Hanlon, S., Kowalczyk, O. S., Kostara, A., Mathew, J., Agbedjro, D., Wexler, B. E., Cohen Kadosh, R., Asherson, P., & Rubia, K. (2021). Transcranial direct current stimulation (tDCS) combined with cognitive training in adolescent boys with ADHD: A double-blind, randomised, sham-controlled trial. Psychological Medicine, 1–16. https://doi.org/10.1017/S0033291721001859
Yamada, Y., & Sumiyoshi, T. (2021). Neurobiological Mechanisms of Transcranial Direct Current Stimulation for Psychiatric Disorders; Neurophysiological, Chemical, and Anatomical Considerations. Frontiers in Human Neuroscience, 15, 631838. https://doi.org/10.3389/fnhum.2021.631838
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